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Retatrutide—A Game Changer in Obesity Pharmacotherapy
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retatrutide is a novel triple agonist peptide at the glucagon receptor, GIP receptor, and GLP-1 receptor. 22-24% weight loss at 48 weeks with a similar tolerability profile to #tirzepatide. @LillyPad #medtwitter #endotwitter
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Diagram showing the mechanism of action of retatrutide
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Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide
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